She appeared in "Passion Patties", where she was on a diet but tried a Passion Patty. As a result, she became addicted. When the spies delivered their cookies to her, she had became incredibly obese due to eating a huge number of cookies. She stated that she had quit her job just so she wouldn't miss any deliveries. She lost the excess weight with the help of WOOHP's antidote.
- Shirley is a reference to the ideal stereotypical United States housewife of the 1950's. Specifically, the ideal emphasized during the baby boom.